Israel has said it will allow Egypt to deliver limited quantities of humanitarian aid to the Gaza Strip.

The first crack in a punishing 10-day siege on the territory came a day after a deadly blast at a Gaza City hospital killed hundreds and put immense strain on Gaza doctors treating the many wounded as medical supplies ran out.

The announcement to allow water, food and other supplies came as rage over Tuesday night’s blast at al Ahli Hospital spread across the Middle East, and as US President Joe Biden visited Israel in hopes of preventing a wider conflict in the region.

Prime Minister Benjamin Netanyahu’s office said the decision was approved after a request from Mr Biden.

Mr Biden said Egypt’s president agreed to open the crossing and, to begin with, to let in 20 trucks with humanitarian aid.

If Hamas confiscates aid, “it will end”, he said. White House officials said the aid would flow as early as Friday, once the roads are patched.

At the Rafah crossing, Gaza’s only connection to Egypt, truckloads of aid have been waiting for days to enter. But the facility has only a limited capacity, and Egypt says it has been damaged by Israeli air strikes.

US President Joe Biden
US President Joe Biden visited Israel (Miriam Alster/pool photo via AP)

Asked if foreigners and dual nationals seeking to leave would be let through, he said: “As long as the crossing is operating normally and the (crossing) facility has been repaired.”

The war started when Hamas militants rampaged across communities in southern Israel on October 7.

There were conflicting claims of who was responsible for the explosion at the hospital. Hamas officials in Gaza quickly blamed an Israeli air strike, saying nearly 500 were killed.

Israel-Hamas war: key locations
(PA Graphics)

The Associated Press has not independently verified any of the claims or evidence released by the parties.

Upon his arrival, Mr Biden embraced Mr Netanyahu — and expressed concern for the suffering of Gaza’s civilians. He later said the hospital blast appeared not to be Israel’s fault.

Mr Biden said data from his defence department showed it was not likely a strike by the Israeli military.

And a National Security Council spokesperson later posted on social media that an analysis of “overhead imagery, intercepts and open source information” showed that Israel was not behind the attack. But the US continued to collect evidence.

“Based on what I’ve seen, it appears as though it was done by the other team, not you,” Mr Biden told Mr Netanyahu in remarks in front of the media.

Israel Palestinians
Smoke rises following an Israeli air strike in the Gaza Strip (Ariel Schalit/AP)

Israeli strikes on Gaza continued on Wednesday, including on cities in south Gaza that Israel had described as “safe zones” for Palestinian civilians.

After the hospital blast, Jordan cancelled a meeting between Mr Biden, Jordan’s King Abdullah II, Palestinian President Mahmoud Abbas and Egyptian President Abdel Fattah El-Sisi. Mr Biden was now visiting only Israel.

The war between Israel and Hamas was “pushing the region to the brink”, Jordanian foreign minister Ayman Safadi told state-run television.

The Israeli military held a briefing on Wednesday morning laying out its case for why it was not responsible for the explosion at the al Ahli Hospital.

Israeli military spokesman Rear Adm Daniel Hagari said it was not firing in the area when the blast occurred.

The misfired rocket hit the car park outside the hospital, he said. Were it an air strike, there would have been a crater there, instead, the fiery blast came from the misfired rocket’s warhead and its unspent propellant, he added.

The Israeli military also released a recording they said was between two Hamas militants discussing the blast, during which the speakers say it was believed to be an Islamic Jihad misfire.

Rear Adm Hagari said Israeli’s intelligence would be shared with US and British officials. He also questioned the death toll provided by Gaza’s Hamas-led Health Ministry.

Since the war began, roughly 450 rockets fired at Israel by militant groups had landed in Gaza, the Israeli military said.

Israel Palestinians
Wounded Palestinians at the al Shifa hospital in Gaza City following Israeli air strikes (Abed Khaled/AP)

The group pointed to Israel’s order that al Ahli be evacuated and reports of a previous strike at the hospital as proof that the hospital was an Israeli target. It also said the scale of the explosion, the angle of the bomb’s fall and the extent of the destruction all pointed to Israel.

The Anglican bishop of Jerusalem, Hosam Naoum, said the hospital, run by the Episcopal Church, had received at least three Israeli military orders to evacuate in the days before the blast.

It was hit by Israeli shelling on Sunday, wounding four staffers, he said. Israel had ordered all 22 hospitals in northern Gaza to evacuate last week.

He declined to cast blame on either party for the blast, saying: “As people of the cloth, we are not military experts. We just want to let people see what is happening on the ground and hope that people will come to the conclusion that we’ve had enough of this war.”

Israel Palestinians
Palestinians inspect the damage at al Ahli hospital in Gaza City (Abed Khaled/AP)

On Wednesday morning, the blast scene was littered with charred cars and the ground was blackened by debris.

Video after the blast showed the hospital grounds strewn with bodies, many of them young children.

Some 350 casualties from the al Ahli blast were rushed to Gaza City’s main hospital, al Shifa, which was already overwhelmed with wounded from other strikes, said its director, Mohammed Abu Selmia. He said doctors were performing surgery on patients lying on floors.

“We need equipment, we need medicine, we need beds… we need everything,” Mr Abu Selmia said. He warned that fuel for the hospital’s generators would run out within hours.

Israel Palestinians Daily Photo Gallery
A man sits outside a building destroyed by an Israeli bombardment at the Rafah refugee camp in the Gaza Strip (Fatima Shbair/AP)

The Gaza Health Ministry said 3,478 people have been killed in Gaza and more than 12,000 wounded, with most of the casualties women, children and the elderly. Another 1,300 people across Gaza are believed to be buried under the rubble, alive or dead, health authorities said.

More than 1,400 people in Israel have been killed, mostly civilians killed during Hamas’s deadly incursion, which resulted in some 200 hostages being taken into Gaza. Militants in Gaza have launched rockets every day since towards cities across Israel.

With troops massed along the border, Israel has been expected to launch a ground invasion into Gaza, though military officials say no decision has been made.

A strike on a three-storey building in Gaza City on Wednesday killed 40 people and another on a bakery in the Nuseirat refugee camp in central Gaza killed four bakers, according to witnesses.

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Palestinians carrying belongings leave the al Ahli hospital, where they had been taking shelter (Abed Khaled/AP)

“It’s not just that people are going hungry. People are at the risk of starvation,” said Alia Zaki, a spokesperson for the World Food Programme.

More than one million Palestinians have fled their homes — roughly half of Gaza’s population — and 60% are now in the approximately eight-mile long area south of the evacuation zone, the UN said.