Captain Pierce Phillips is absent through injury, as is vice-captain James Freeman, but hooker Joe Buckle is rotated out of the match-day squad after starting the last two Championship games. Flanker James Doyle is handed his first competitive start for the Reds, as is Jordan Davies, who comes in in place of Lewis Robling at inside centre.
Nick Selway starts at hooker, Nick Campbell returns to the second row, while Sami Fisilau is handed the number nine jersey for the first time this season.
Biljon said: ‘We had some pre-meditated changes because we have to make sure we keep finding that balance with regards to giving players game time.’
The match kicks-off at 2 pm.
1-15: Marc Thomas, Nick Selway, Simon Kerrod, Nick Campbell, Dave McKern, Max Argyle, James Doyle, Nick Haining; Sami Fisilau, Brendan Cope; Ross Adair, Jordan Davies, Regan King (c), George Watkins, Jack Cuthbert. Replacements: Jack Macfarlane, Jake Woolmore, Jake Armstrong, James Voss, Uili Kolo’ofa’i, Kieran Hardy, Lewis Robling.
